Cav1 ELISA Kit for Mouse(Mus musculus) | EIAab.comCav1 ELISA Kit for Mouse(Mus musculus)

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Cav1 (Gene name),

Caveolin-1 (Protein name ), CAV1_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

Related Databases

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Gene name:

Cav1(Cav);

Protein name:

Caveolin-1;

Alternative:

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Homooligomer (By similarity). Interacts (via the N-terminus) with DPP4; the interaction is direct (By similarity). Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Interacts with BMX, BTK, CTNNB1, CDH1, GLIPR2, JUP, NOSTRIN, SNAP25 and STX1A.

Function:

Involved in the costimulatory signal essential for T-cell receptor (TCR)-mediated T-cell activation. Its binding to DPP4 induces T-cell proliferation and NF-kappa-B activation in a T-cell receptor/CD3-dependent manner. May act as a scaffolding protein within caveolar membranes. Interacts directly with G-protein alpha subunits and can functionally regulate their activity. Forms a stable heterooligomeric complex with CAV2 that targets to lipid rafts and drives caveolae formation. Recruits CTNNB1 to caveolar membranes and may regulate CTNNB1-mediated signaling through the Wnt pathway.

Subcellular Location:

Golgi apparatus membrane Peripheral membrane protein Cell membrane Peripheral membrane protein Membrane caveola Peripheral membrane protein Membrane raft Colocalized with DPP4 in membrane rafts. Potential hairpin-like structure in the membrane. Membrane protein of caveolae.

Protein Attributes:

Sequence length:

178

Sequence:

50:

100:

150:

178:

YVHTFCDPLF | EAIGKIFSNI | RISTQKEI

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:12389

String:

P49817

Pfam:

PF01146

UniGene:

Mm.28278

Uniprot:

P49817

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ELISA Kit for Mouse Caveolin-1

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E0214h

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ELISA Kit for Mouse Caveolin-1

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E0214r

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ELISA Kit for Mouse Caveolin-1

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E0214b

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ELISA Kit for Mouse Caveolin-1

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E0214m

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ELISA Kit for Mouse Caveolin-1

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E0214p

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ELISA Kit for Mouse Caveolin-1

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E0214c

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ELISA Kit for Mouse Caveolin-1

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ELISA Kit for Mouse Caveolin-1

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E0214d

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96T

CLIA Kit for Mouse Caveolin-1

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U0214p

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96T

CLIA Kit for Mouse Caveolin-1

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U0214r

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96T

CLIA Kit for Mouse Caveolin-1

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U0214b

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96T

CLIA Kit for Mouse Caveolin-1

Cat.:

U0214m

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96T

CLIA Kit for Mouse Caveolin-1

Cat.:

U0214c

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96T

CLIA Kit for Mouse Caveolin-1

Cat.:

U0214h

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96T

CLIA Kit for Mouse Caveolin-1

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U0214d

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CLIA Kit for Mouse Caveolin-1

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Polyclonal Antibody for Mouse Caveolin-1

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P0214Rb-h

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40ug/0.2ml

Polyclonal Antibody for Mouse Caveolin-1

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P0214Rb-m

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Polyclonal Antibody for Mouse Caveolin-1

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P0214Rb-r

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Monoclonal Antibody for Mouse Caveolin-1

Protein for Mouse Caveolin-1

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

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Recovery

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Linearity

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References

1.

"The primary sequence of murine caveolin reveals a conserved consensus site for phosphorylation by protein kinase C."
Tang Z. , Scherer P.E. , Lisanti M.P.
Gene147:299-300(1994) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: BALB/c.
2.

"Caveolin-1 isoforms are encoded in distinct mRNAs: identification of mouse caveolin-1 mRNA variants caused by alternative transcription initiation and splicing."
Kogo H. , Fujimoto T.
FEBS Lett.465:119-123(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [GENOMIC DNA / MRNA] (ISOFORMS 1 AND 2)
3.

"Met gene is a candidate for the mouse pulmonary adenoma resistance 4 (Par4) locus."
Zaffaroni D. , Dragani T.A.
Submitted (2003-10) to the EMBL/GenBank/DDBJ databases

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] (ISOFORM 1)
strain: SWR/J.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2)
strain: C57BL/6J.
tissue: Embryo.
tissue: Skin.
tissue: Urinary bladder.
5.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORM 1)
strain: C3H/He.
tissue: Mesenchymal cell.
6.

"Caveolin isoforms differ in their N-terminal protein sequence and subcellular distribution. Identification and epitope mapping of an isoform-specific monoclonal antibody probe."
Scherer P.E. , Tang Z. , Chun M. , Sargiacomo M. , Lodish H.F. , Lisanti M.P.
J. Biol. Chem.270:16395-16401(1995) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PROTEIN SEQUENCE OF 5-26; 47-77 AND 165-176
7.

"Caveolin-1 expression inhibits Wnt/beta-catenin/Lef-1 signaling by recruiting beta-catenin to caveolae membrane domains."
Galbiati F. , Volonte D. , Brown A.M. , Weinstein D.E. , Ben-Ze'ev A. , Pestell R.G. , Lisanti M.P.
J. Biol. Chem.275:23368-23377(2000) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: FUNCTION
8.

"The insulin receptor catalyzes the tyrosine phosphorylation of caveolin-1."
Kimura A. , Mora S. , Shigematsu S. , Pessin J.E. , Saltiel A.R.
J. Biol. Chem.277:30153-30158(2002) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-14
9.

"c-Abl is required for oxidative stress-induced phosphorylation of caveolin-1 on tyrosine 14."
Sanguinetti A.R. , Mastick C.C.
Cell. Signal.15:289-298(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: PHOSPHORYLATION AT TYR-14
10.

"Immunoaffinity profiling of tyrosine phosphorylation in cancer cells."
Rush J. , Moritz A. , Lee K.A. , Guo A. , Goss V.L. , Spek E.J. , Zhang H. , Zha X.-M. , Polakiewicz R.D. , Comb M.J.
Nat. Biotechnol.23:94-101(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
11.

"Large scale localization of protein phosphorylation by use of electron capture dissociation mass spectrometry."
Sweet S.M. , Bailey C.M. , Cunningham D.L. , Heath J.K. , Cooper H.J.
Mol. Cell. Proteomics8:904-912(2009) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.
12.

"Essential role of PACSIN2/syndapin-II in caveolae membrane sculpting."
Senju Y. , Itoh Y. , Takano K. , Hamada S. , Suetsugu S.
J. Cell Sci.124:2032-2040(2011) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH PACSIN2;SUBCELLULAR LOCATION
13.

"SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways."
Park J. , Chen Y. , Tishkoff D.X. , Peng C. , Tan M. , Dai L. , Xie Z. , Zhang Y. , Zwaans B.M. , Skinner M.E. , Lombard D.B. , Zhao Y.
Mol. Cell50:919-930(2013) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: ACETYLATION [LARGE SCALE ANALYSIS] AT SER-2 AND LYS-5;IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS];CLEAVAGE OF INITIATOR METHIONINE [LARGE SCALE ANALYSIS]
tissue: Embryonic fibroblast.

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